Effects of Lycopene on the Susceptibility of Low-Density Lipoproteins to Oxidative Modification

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چکیده مقاله:

The intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. To clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (LDL) to oxidative modification. In this study, “lycopene” was added to plasma and incubated for 3 h at 37°C. Then, the LDL fraction was separated by ultracentrifugation. The oxidizability of LDL was estimated by measuring conjugated dienes (CD), lipid peroxides and thiobarbituric acid-reactive substances (TBARS) after addition of cupric sulfate solution. We showed that lycopene significantly (P

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effects of lycopene on the susceptibility of low-density lipoproteins to oxidative modification

the intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. to clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (ldl) to oxidative modification. in this study, “lycopene” was added to plasma and incubated...

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عنوان ژورنال

دوره Volume 6  شماره Number 3

صفحات  173- 177

تاریخ انتشار 2010-11-20

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